The latest collection of commentary and Essays in @PLOSBiology is devoted to #immunometabolism.
We highlight how the interplay between systemic metabolism and the immune response impact tissue and organismal functions, as well as the therapeutic potential of manipulating immunometabolism.
鈿涳笍 Nicole Chapman and Hongbo Chi advocate for the use of systems biology approaches as discovery tools for new therapeutic targets
馃拤 Yun Sok Lee investigates the process of metaflammation, the chronic low-grade inflammatory response that occurs in metabolic diseases such as obesity and type 2 diabetes, exploring how systemic changes in metabolism can affect tissue-resident immune cells
馃 Griffin Gowdy and Alice Prince look at the role of immunometabolites in both driving and combating bacterial infections, with a focus on lung pathogens
馃 On a more holistic level, Guang Sheng Ling and colleagues suggest a two-pronged approach to target immunometabolism through pharmaceutical and lifestyle interventions, with a focus on cancer
The collection was edited by Claudio Mauro, Lucas Smith and Joanna Clarke
#immunology #metabolism #cancer #aging #inflammation #infection
https://collections.plos.org/collection/facets-of-immunometabolism/
