@cmyrland Mostly no. The one risk would be that it's using ammonium nitrate, which can release ammonia gas when it dissolves.
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@brianb
Nice, thanks. I'll have to take a closer look at the ice packs we have, but even if there's some ammonia gas, I'm thinking the amount of gas produced by the contents of one bag won't be a big issue as long as the room is well ventilated, or we're doing it outside?