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Strypey
@strypey@mastodon.nzoss.nz  ·  activity timestamp 3 weeks ago

(1/?)

@CatherineOrganic1
> Patent law in medicine means good medicines are dumped for the new and unproven

Indeed. Also there's a powerful incentive to fund research into novel chemicals or equipment that might get patents. But little or no incentive to research generic plant medicines, or non-medicinal treatments, which probably won't. Even where there's good reason to believe they might be more effective and cheaper to provide.

#patents #DrugPatents

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Strypey
@strypey@mastodon.nzoss.nz replied  ·  activity timestamp 3 weeks ago

(2/?)

Antidepressants are a great example. Every 20 years or so the dominant Antidepressants starts to be loudly criticised over safety or efficacy, and dumped. In favour of new, freshly patented drugs.

Meanwhile, vitamin D is a very effective treatment in some cases, especially for seasonal depression. But it remains chronically understudied. So not subsidised by public health systems, while novel pharmaceutical antidepressants are, despite significant evidence of harm in many cases.

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Strypey
@strypey@mastodon.nzoss.nz replied  ·  activity timestamp 3 weeks ago

(3/?)

@CatherineOrganic1
> The alltrials transparency push looks good but again rules without enforcement mean nothing

The original AllTrials campaign, started by Dr Ben Goldacre, pushed for drug regulators like the FDA to ignore studies that were not registered before they began. Preventing companies from running dozens of studies behind closed doors, cherry-picking ones that make their products look good for publication and presentation to regulators. Very enforceable.

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Strypey
@strypey@mastodon.nzoss.nz replied  ·  activity timestamp 3 weeks ago

(4/?)

@CatherineOrganic1
> breaking down the science of modified RNA toxicity and its inappropriate use as a 'vaccine' when it is at best a transfection

I'm not sure what this means. Care to expand?

But from your link;

"Dr. James Wilson, the lead investigator, owned stock in Genovo, the company developing the therapy, and stood to gain millions if the therapy was successful."

A classic example of the perverse incentives created by the commercialisation of biological and medical research.

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Strypey
@strypey@mastodon.nzoss.nz replied  ·  activity timestamp 3 weeks ago

(5/5)

@CatherineOrganic1
> definitely not appropriate for use in organics as a veterinary vaccine, hence entering the food supply

💯%. Nothing involving genetic manipulation is appropriate in organic food or medicine production. Not without decades of noncommercial public research, in a sealed environment. To establish narrow, predictable effectiveness, and rule out unanticipated long term side effects.

Even then, the precautionary principle must be paramount.

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r3d0x
@k0nd0r@gigaohm.bio replied  ·  activity timestamp 2 weeks ago
@strypey

I will step in and attempt to satisfy your curiosity about the term "transfection". Since I'm the one who first reached out to you i feel it would be dishonorable not to respond.

The so-called "vaccines" based on the mRNA platform are not a novel technology at all, but rather a permutation of an already existing transfection technology used in academic biology for the last two decades. The commercially available product lipofectamine has already been used in conjuction with mechanical agitation to create lipid nano particles onsite in labs around the world.

Likewise, recombinant RNA techniques in conjunction with their replication in cell culture (commonly referred to as "process 2") is a time tested process for creating large quantities of synthetic RNA molecules. The "novel" mRNA products are marketed as a new technology to circumvent patent law and provide cover for big pharmaceutical corporations to fraudulently reap massive profits from this previously existing intellectual property.

These products are also marketed as vaccines to cover up the fact that this technology of transfection has already been proven to be both useless as a therapy and dangerous in both animals and humans -- best exemplified by the jesse gelsinger case.
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