🧠 New paper by Wimalasena, Pandarinath, AuYong et al: #spinal #interneuron populations form a low-dimensional #manifold that robustly organizes step cycles.
Distinct regions of the manifold mark flexion–extension transitions, and a specific “hold region” tightly controls cycle duration. Deletions emerge as failures to enter the flexor region, giving a dynamical signature of disrupted CPG function.
🌍 https://doi.org/10.1038/s41467-025-64629-y
#Neuroscience #Locomotion #SpinalCord #PopulationDynamics #CompNeuro
Spinal interneuron population dynamics underlying flexible pattern generation
