Apparently, people have become so thoroughly fed up with WhatsApp Desktop and WhatsApp Web that they've reached the "fine, I'll build my own WhatsApp" stage. ZapZap is one of those attempts, built with PyQt6 and QtWebEngine to turn WhatsApp Web into a more proper desktop experience, with things like multiple accounts, native notifications, system tray integration, and more. I haven't tested its accessibility yet, so that's a completely separate adventure.
https://github.com/rafatosta/zapzap