A dense heatmap titled “Vaccines reduced measles cases across US states” showing reported measles cases per 100,000 people in all 50 US states from 1929 to 2022 with color-coded cells on a log scale from dark blue (high incidence, over 1,000 cases per 100,000) through green to pale yellow (low incidence, near zero), with white cells indicating missing data, with three key vertical lines marking major interventions: 1963 for the development of the first measles vaccine by John Enders, 1971 for the development of the measles-mumps-rubella (MMR) vaccine by Maurice Hilleman, and 1980 when vaccination became mandatory for kindergarten entry, showing a clear decline in measles incidence after these milestones with dark blue and green densities fading to mostly pale yellow after the 1980s, indicating near elimination of cases across states.