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eLife
eLife
@eLife@fediscience.org  ·  activity timestamp 4 days ago

This *fundamental* study provides new evidence of a change in how microglia survey neurons during the chronic phase of neurodegeneration. #Neuroscience
https://elifesciences.org/articles/107650?utm_source=mastodon&utm_medium=social&utm_campaign=organic

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eLife

Dissecting surveying behavior of reactive microglia under chronic neurodegeneration

In chronic neurodegeneration associated with prion disease, reactive microglia adopt a highly mobile, neuron-by-neuron surveillance strategy, replacing homeostatic process-based monitoring with dynamic somatic migration and prolonged neuronal engagement.
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