If someone has chronic pain, and your first instinct is to ask "Have you tried--"
Stop.
"Chronic" means ongoing. It means they have been dealing with it for awhile. If they haven't tried something, it's because it's out of their means. Questioning that they haven't tried everything under the sun implies you think they want to be in pain.
If we say we are in pain, we are not asking for advice. We are telling you how the system has failed us. Tell the system, not us, what to do.