In regards to Xena making a statement against the stigma surrounding HIV: in the episode 'Here She Comes... Miss Amphipolis', Xena enters a beauty pageant undercover. There, she encounters Miss Artiphys, a character played by the late Karen Dior, an HIV-positive actor, singer, former adult performer, and drag queen (reports on Dior’s gender identity are contradictory, and probably also affected by '90s culture).

When Xena discovers that Miss Artiphys was an AMAB character who entered the competition presenting as a woman, the latter explains her actions with the line: "You really don’t get it, do you? I guess being born a woman you wouldn’t. This is a chance to use a part of me most people usually laugh at, or worse. A part I usually have to hide. Only here that part works for me, you see?" expecting Xena to force her to drop.

Instead, Xena encourages her to stay in the competition, never reveals her secret, never disrespects her, and in the end, she ends up being crowned winner. After her victory, Xena and Artiphys share a kiss. That was an intentional statement against the widespread misinformation surrounding AIDS and the transmission of HIV that reportedly Lucy Lawless insisted on being included.

It is near impossible to fully explain how ridiculously groundbreaking it was that this entire plot happened in the mid '90s.

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