#Tag
Could you use a little bit of good news?
SARS-CoV-2 mRNA vaccines (like the Pfizer and Moderna COVID-19 vaccines) appear to help cancer patients respond better to immunotherapy treatments.
Paper:
SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade
https://www.nature.com/articles/s41586-025-09655-y
I am fascinated by how viruses evolve - and not just since #SARSCoV2 has shown us at the global stage how consequential virus evolution can be for us.
In my new story in Science I got to explore how researchers are probing deeper into the past with old RNA virus genome.
So a thread…
I am fascinated by how viruses evolve - and not just since #SARSCoV2 has shown us at the global stage how consequential virus evolution can be for us.
In my new story in Science I got to explore how researchers are probing deeper into the past with old RNA virus genome.
So a thread…
I am fascinated by how viruses evolve - and not just since #SARSCoV2 has shown us at the global stage how consequential virus evolution can be for us.
In my new story in Science I got to explore how researchers are probing deeper into the past with old RNA virus genome.
So a thread…
Je viens de faire mes rappels vaccin Covid et Grippe ! ✨
ℹ️ Pensez à le faire aussi pour vous protéger des formes graves
(qui font de sacré dégât à long terme)
et aussi pour protéger les autres en diminuant les risques d’être un relais !
Et autant que possible, pensez au masque FFP2 et à l’aération, ce sont les autres facteurs très efficaces 😃
#covid19 #covid #sarscov2 #grippe
Je viens de faire mes rappels vaccin Covid et Grippe ! ✨
ℹ️ Pensez à le faire aussi pour vous protéger des formes graves
(qui font de sacré dégât à long terme)
et aussi pour protéger les autres en diminuant les risques d’être un relais !
Et autant que possible, pensez au masque FFP2 et à l’aération, ce sont les autres facteurs très efficaces 😃
#covid19 #covid #sarscov2 #grippe
With the NB.1.8.1.* "Nimbus" and XFG.* "Stratus" variants carving up dominance around the globe, it is time to ponder which variant might drive the next wave.
The leading contender at this point is PY.1.1.1. It is still at a low frequency in the global view, but is already widespread geographically and showing strong recent growth.
XFG.1.1 is showing strong recent growth.
I added some other contenders for monitoring, although they don’t seem significant so far: XEC.27.2.*, XFV, XFW, XFZ and XGA.
With the NB.1.8.1.* "Nimbus" and XFG.* "Stratus" variants carving up dominance around the globe, it is time to ponder which variant might drive the next wave.
The leading contender at this point is PY.1.1.1. It is still at a low frequency in the global view, but is already widespread geographically and showing strong recent growth.
XFG.1.1 is showing strong recent growth.
I added some other contenders for monitoring, although they don’t seem significant so far: XEC.27.2.*, XFV, XFW, XFZ and XGA.
Postural orthostatic tachycardia syndrome in post-COVID-19 long-hauler patients is associated with platelet storage pool deficiency
https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2025.1560120/full
"most #POTS patients have a platelet delta granule storage pool deficiency"
Image is screenshot from latest Science for ME weekly update
@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
#Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2 @pots
Postural orthostatic tachycardia syndrome in post-COVID-19 long-hauler patients is associated with platelet storage pool deficiency
https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2025.1560120/full
"most #POTS patients have a platelet delta granule storage pool deficiency"
Image is screenshot from latest Science for ME weekly update
@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
#Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2 @pots
So I'm reading https://www.medrxiv.org/content/10.1101/2025.08.08.25333305v1.full-text with interest as it ostensibly found metformin didn't meaningfully decrease Long COVID rates
and
participants didn't receive the metformin until a median five days after symptom onset
they cite other work that found a ~40% reduction in LC with metformin dose:
In the COVID-OUT randomized trial, the HR for participant-reported clinician diagnosis of LC in those randomized to 14 days of metformin was 0.59 (95% CI 0.39 to 0.89)
and I am left wondering if maybe "metformin should be taken as early as possible during acute COVID-19" is what the new study really suggests
#SARSCoV2#COVID#COVID19 #LongCOVID #metformin #CovidIsNotOver
Someone (you know who you are) pointed this https://www.sciencedirect.com/science/article/pii/S2589004224018959 out
which hints that maybe metformin's mechanism of action against LC might be to make it harder for C19 to establish viral reservoirs
haven't read the paper in depth but a very interesting notion
if true then we could expect to see meformin
So I'm reading https://www.medrxiv.org/content/10.1101/2025.08.08.25333305v1.full-text with interest as it ostensibly found metformin didn't meaningfully decrease Long COVID rates
and
participants didn't receive the metformin until a median five days after symptom onset
they cite other work that found a ~40% reduction in LC with metformin dose:
In the COVID-OUT randomized trial, the HR for participant-reported clinician diagnosis of LC in those randomized to 14 days of metformin was 0.59 (95% CI 0.39 to 0.89)
and I am left wondering if maybe "metformin should be taken as early as possible during acute COVID-19" is what the new study really suggests
#SARSCoV2#COVID#COVID19 #LongCOVID #metformin #CovidIsNotOver
"A growing number of scientists believe that the SARS-CoV-2 virus may instead be subtly altering our immune systems. If correct, their hypothesis will change how we understand everything from respiratory syncytial virus (RSV) to shingles to sepsis."
God damn, finally.
"A growing number of scientists believe that the SARS-CoV-2 virus may instead be subtly altering our immune systems. If correct, their hypothesis will change how we understand everything from respiratory syncytial virus (RSV) to shingles to sepsis."
God damn, finally.
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