Does human episodic memory 🧠 depend on context-invariant or conjunctive coding of single neurons in the human hippocampus?

A recent TiCS (https://www.cell.com/trends/cognitive-sciences/fulltext/S1364-6613(25)00031-2) paper stimulated a very interesting debate about the nature of hippocampal coding in human episodic memory that i found very insightful.

The discussion centers around context-invariant coding of concept neurons (CN) vs. conjunctive coding of episode-specific neurons (ESN) in the hippocampus, both following different lines of thinking about the HCs involvement in episodic memory.

A short 🧵
1/5

#hippocampus #neuroscience #memory #brain

Does human episodic memory 🧠 depend on context-invariant or conjunctive coding of single neurons in the human hippocampus?

A recent TiCS (https://www.cell.com/trends/cognitive-sciences/fulltext/S1364-6613(25)00031-2) paper stimulated a very interesting debate about the nature of hippocampal coding in human episodic memory that i found very insightful.

The discussion centers around context-invariant coding of concept neurons (CN) vs. conjunctive coding of episode-specific neurons (ESN) in the hippocampus, both following different lines of thinking about the HCs involvement in episodic memory.

A short 🧵
1/5

#hippocampus #neuroscience #memory #brain

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